Thyroid function
Sets resting metabolic rate. Hypothyroidism is common, often undiagnosed, and will quietly work against any plan that never checked for it.
Medical Weight Loss · Hinsdale, Illinois
GLP-1 medications can help. What decides whether they help you, and whether any result lasts, is what else is going on underneath: thyroid, insulin, cortisol, lipids, testosterone, sleep. We measure all of it in one 90-minute visit, in our own CLIA-certified lab, before anyone writes a prescription.
Completing an assessment does not guarantee a prescription. All treatment decisions are made by the treating clinician based on your history, evaluation, and applicable standards of care. Adults 18+.











As featured in










Why we start here
Appetite and willpower are the two variables everyone starts with. They are seldom the ones that matter most. These are the others, and every one of them is measurable in a single morning.
Sets resting metabolic rate. Hypothyroidism is common, often undiagnosed, and will quietly work against any plan that never checked for it.
Fasting glucose can read normal for years while fasting insulin climbs. Measuring both shows how hard the body is working to hold that normal number.
Testosterone, SHBG and estradiol shape body composition, recovery and appetite signaling, and how much lean mass survives a period of weight loss.
Chronic stress changes where the body stores fat, how well it sleeps, and how it responds to training. It is measurable rather than assumed.
Obstructive sleep apnea is common in adults carrying excess weight and frequently undiagnosed. Untreated, it is associated with poorer metabolic health.
Some prescriptions promote weight gain. Low vitamin D, low ferritin and anemia all sap the energy a plan depends on. Both are simple to check.
You cannot guess which of these applies to you, and treating the wrong one costs a year. That is why what you book on this page is the Alpha Performance Assessment: 150+ clinical markers across all six systems in one 90-minute visit, rather than a weight-loss consultation. A GLP-1 medication may well be part of the answer. The assessment is what tells your clinician whether it is, and what else needs attention alongside it.
The process
No 30-day onboarding funnel. No chat-only clinician you never meet.
Pick a specific appointment online in under a minute. Nothing is due to book. The $497 is paid at your visit.
Blood draw on site, body composition on the InBody 970, grip strength, blood pressure, stadiometer. Your hormone panel runs in our lab while you are still in the building.
Key findings are walked through with your context in the room: what is driving the number, what it means, and what the realistic options are. Remaining results are incorporated as they return.
If your results and evaluation support it, treatment can begin at the same visit. If they don't, we will tell you that instead, and tell you what to address first.
What gets measured
Weight is an output. These are the inputs. Each is reviewed against your history and symptoms by a clinician: a number outside a reference range is a question, not a diagnosis.
Choose Your TimeA1c, fasting insulin, glucose, HOMA-IR, uric acid
Total & free testosterone, SHBG, estradiol, LH, FSH, DHEA-S
TSH, free T4, free T3, reverse T3, antibodies
ApoB, Lp(a), full lipid panel, hs-CRP, blood pressure
Hepatic and renal panels, CBC, ferritin, vitamin D, B12
InBody 970 lean mass, visceral fat, phase angle, grip strength
Panel composition is determined by the clinical team and may vary based on your history, symptoms, and medical appropriateness. Counts shown are representative of a typical assessment.
An honest comparison
All three are legitimate. They are not the same product.
| Alpha Refinery | App-based GLP-1 subscription | Primary care visit | |
|---|---|---|---|
| Intake | 90-minute in-person clinical evaluation | Online questionnaire, often asynchronous | 15–20 minute appointment |
| Labs before first dose | 61 biomarkers, run in our own CLIA lab | Varies, sometimes optional or self-reported | Typically a basic metabolic panel and A1c |
| Time to results | Key findings same day | Days to weeks by portal | Days by portal or follow-up call |
| Body composition | InBody 970, lean mass tracked, not just weight | Not included | Rarely included |
| Hormone & thyroid workup | Included | Usually separate or unavailable | By referral |
| Sleep apnea screening | Optional at-home study, +$297 | Not included | By referral to a sleep center |
| Commitment | One assessment, no required enrollment | Recurring monthly subscription | Co-pay per visit |
| Who adjusts your dose | Your prescriber, on a schedule | Varies by platform | Your physician |
| Insurance | Cash-pay; HSA/FSA receipts provided | Typically cash-pay | Billed to insurance; coverage for weight-loss medication varies |
Comparison describes Alpha Refinery's own process versus common industry models as of 2026 and is provided for general information. Other providers' offerings vary; evaluate any program on its own terms. No comparison of clinical outcomes is expressed or implied.
Obstructive sleep apnea is common in adults carrying excess weight, and it is frequently undiagnosed. It is also bidirectional: untreated apnea is associated with poorer metabolic health, and weight change can alter apnea severity in either direction. Screening for it before a year-long metabolic plan is simply good medicine.
Add the WatchPAT ONE home sleep test to your assessment. You sleep one night in your own bed. Results are typically available within 24 hours and are reviewed alongside your labs.
A home sleep test is a screening tool. It does not diagnose every sleep disorder, and your clinician may recommend an in-lab study instead. The $297 test is paid on a follow-up call before the device ships, and cannot be refunded once it ships.
Pricing
We are a cash-pay practice and we do not bill insurance. You will know the number before you book.
150+ clinical markers · 61 blood biomarkers · 90-minute private visit · same-day review of key findings
Medication, if prescribed, is billed separately and is not included in the assessment fee. Cost depends on the medication selected and your pharmacy.
Cancellation: nothing is due to book, so there is nothing to refund. Please give us at least two business days’ notice to cancel or move your visit. The sleep study’s $297 is paid on a follow-up call before the device ships and cannot be refunded once it ships.
No guarantee of treatment: purchasing or completing an assessment does not guarantee that you will receive a prescription, medication, or any particular treatment. All treatment decisions are made independently by the treating clinician.
Patient reviews
"I'm 56 and I've been to other men's health clinics that either feel way too clinical or lean too heavy into the 'bro' vibe. Alpha Refinery is completely different."
"The team took the time to explain my options and I never felt rushed. Easily the best experience I've had."
"Getting the labs and the conversation in the same visit changed how seriously I took the plan."
Reviews reflect the experiences of individual patients and are not a promise or guarantee of any particular result. Individual results vary.
Who you'll see
Wesley Nahm, MDMedical Director
Brad Simmons, FNP-BC, APRN-FPAClinical Director
Lisa Bakken, MBA, MLS(ASCP)CMDirector of LaboratoryAlpha Refinery is a licensed medical practice in Hinsdale, Illinois, approved by the Illinois Department of Financial and Professional Regulation and certified by LegitScript. Services are available to adults 18 and older located in Illinois.
Inside the practice
Private entrance, unhurried appointments, and a laboratory on site. This is where your assessment happens.





Important safety information
Read this before you book. If any of it applies to you, bring it up at your visit. It changes the recommendation.
GLP-1 receptor agonists such as semaglutide and tirzepatide carry a boxed warning for thyroid C-cell tumors based on rodent studies. They are contraindicated in people with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2, and in anyone with a known serious hypersensitivity to the drug or its components. They are not indicated for type 1 diabetes and are not for use during pregnancy or while trying to become pregnant.
The medications prescribed here are compounded preparations from licensed compounding pharmacies, prescribed only where a clinician determines a compounded formulation is clinically appropriate for that patient. Compounded drugs are not FDA-approved. The FDA does not review them for safety, effectiveness, or manufacturing quality, and they are not rated as therapeutically equivalent to any brand-name product. Risks associated with the underlying active ingredients, including everything described above, still apply.
Published clinical trials report average weight reductions over 68–72 weeks in adults with obesity or overweight: approximately 15% with semaglutide 2.4 mg (STEP 1, Wilding et al., NEJM 2021) and approximately 21% with tirzepatide 15 mg (SURMOUNT-1, Jastreboff et al., NEJM 2022). In both trials, all participants (including those on placebo) also received lifestyle intervention. These are trial averages, not predictions. Individual results vary substantially, some people do not respond, and weight regain after discontinuation is common and documented. Both trials studied FDA-approved branded products, not compounded preparations. Results from those trials should not be assumed to apply to a compounded medication.
The information here is general and educational. It is not a substitute for a medical evaluation, diagnosis, or treatment by a licensed clinician, and no clinician-patient relationship is created by reading it or by submitting a form. Medication is prescribed only when a licensed clinician determines it is medically appropriate for you after an evaluation. Full prescribing information for any medication discussed is available from the manufacturer and will be reviewed with you.
Questions
That is a clinical determination, and it is the actual purpose of the assessment. Clinicians generally consider factors including BMI, weight-related health conditions, your medical and family history, current medications, and lab findings. Some people are clearly appropriate candidates. Some have a thyroid, sleep, or medication issue that should be addressed first. Some should not take these medications at all. We will tell you which of those you are, in plain language, at the visit.
The honest answer is that it varies widely and nobody can promise you a number. What we can point to is published trial data: in STEP 1 (NEJM, 2021) adults on semaglutide 2.4 mg lost an average of about 15% of body weight over 68 weeks, and in SURMOUNT-1 (NEJM, 2022) adults on tirzepatide 15 mg lost an average of about 21% over 72 weeks. Both trials paired the medication with lifestyle intervention for every participant.
Those are averages across thousands of people. Your result depends on your starting physiology, the dose you tolerate, your protein and training habits, your sleep, and how long you stay on therapy. Individual results vary, and we will not quote you a target number to get you in the door.
For patients who qualify after their evaluation, we prescribe compounded semaglutide or tirzepatide, prepared by a licensed compounding pharmacy. We do not dispense brand-name products.
Compounded medications are not FDA-approved. The FDA does not review compounded preparations for safety, effectiveness, or manufacturing quality, and they are not rated as therapeutically equivalent to any brand-name product. Your prescriber will tell you exactly what is being prescribed, which pharmacy it comes from, the dosing schedule, the risks, and the cost before you start, and whether a compounded preparation is clinically appropriate for you at all.
The Alpha Performance Assessment is $497, paid at your visit. Nothing is due to book. The optional WatchPAT ONE home sleep study is an additional $297, paid on a follow-up call before the device ships.
We are a cash-pay practice and do not bill insurance. We provide itemized receipts suitable for HSA and FSA submission. Medication, if prescribed, is billed separately by your pharmacy; coverage for weight-management medication varies significantly by plan and many plans exclude it.
You don't need them to lose weight. You need them to know why it has been hard, whether a medication is safe for you, and what will happen when you come off it. Undiagnosed hypothyroidism, insulin resistance, low testosterone, anemia, vitamin D deficiency, and untreated sleep apnea all affect energy, appetite, training capacity, and body composition, and all of them are findable in a morning.
It also gives you a real baseline. When we repeat markers later, you can see what changed beyond the scale, including whether you are holding onto lean mass.
There is no universal answer, and any clinic that gives you one is guessing. Some people use a GLP-1 for a defined period and transition off with a structured taper. Others, particularly those with weight-related metabolic conditions, may be on therapy longer under continued clinical supervision.
What the evidence does show clearly is that weight regain after stopping is common. That is precisely why the clinical protocol we build with you covers protein intake, resistance training, sleep, and follow-up labs, the maintenance phase is discussed before you start, not after.
Our clinicians are licensed in Illinois, and we care for patients located in Illinois. We are not able to treat patients outside the state.
The assessment itself is performed at our Hinsdale office, and that is by design: the blood draw, the on-site same-day lab processing, body composition on the InBody 970 and grip strength all require you to be in the building. If you are in Illinois but a long drive from Hinsdale, call us first and we will walk you through exactly what the visit involves before you commit to a time.
It is optional. It is also, for a lot of patients, the most useful $297 they spend. Obstructive sleep apnea is common in adults carrying excess weight and frequently goes undiagnosed for years. Untreated, it is associated with poorer metabolic health, daytime fatigue, and reduced training capacity, all of which work against a weight-management plan.
The WatchPAT ONE is a single-night, at-home, FDA-cleared device. Results are typically available within 24 hours and are interpreted alongside your labs. A home sleep test is a screening tool; your clinician may still recommend an in-lab study depending on findings.
No. Purchasing or completing an assessment does not guarantee that you will receive a prescription, medication, or any particular treatment. All treatment decisions are made independently by the treating clinician based on your medical history, evaluation, diagnostic findings, clinical judgment, and applicable standards of care. If a medication is not appropriate for you, we will say so and tell you what we would do instead.
Alpha Performance Assessment · Hinsdale, Illinois
Choose your visit, then choose your time. Nothing is due to book, and nothing about why you are coming is asked online.
Prefer to speak with someone first? Call (630) 242-1330
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HSA & FSA Eligible
Nothing due to book. Paid at your visit.
LegitScript Certified
IDFPR approved · CLIA-certified lab
Easy Rescheduling
Two business days’ notice to cancel or move
12 Salt Creek Lane, Suite 350
Hinsdale, IL 60521
Private entrance
Mon, Thu, Fri 9am–5pm
Tuesday 7am–3pm 7AM
Wednesday 11am–7pm 7PM
Sat & Sun closed
(630) 242-1330
Cash-pay practice; insurance is not billed
What you are booking is the Alpha Performance Assessment, a diagnostic evaluation, not a prescription. Completing an assessment does not guarantee that you will receive a prescription, medication, or any particular treatment. All treatment decisions are made independently by the treating clinician based on your medical history, evaluation, diagnostic findings, clinical judgment, and applicable standards of care. Services are for adults 18 and older. Do not use this booking form for medical emergencies. Call 911.